Recurrent miscarriage evaluation

Miscarriage Evaluation & Recurrent Pregnancy Loss (RPL) — Sharjah

At American Fertility Centre — Sharjah, our Miscarriage Evaluation Service offers a sensitive, evidence-based pathway to identify causes of pregnancy loss and reduce recurrence risk. We combine prompt tissue testing, genetic analysis, endocrine and immunologic screening, uterine imaging and multidisciplinary counselling so couples understand why a loss happened and what the next safe step should be.

Overview — why evaluation matters
Most early miscarriages are sporadic and frequently due to random chromosomal errors, but when losses repeat, targeted investigation can often identify treatable causes or inform personalised care. Definitions vary by society, but modern guidelines use two or more pregnancy losses as the threshold to begin RPL evaluation while recognising clinical context matters. Early, structured evaluation reduces uncertainty and directs appropriate interventions.

Who should be evaluated?
We recommend a miscarriage evaluation for people who have:
Experienced two or more confirmed clinical pregnancy losses (including intrauterine miscarriages) or, in some situations, one loss with clear risk factors.
Suffered a late miscarriage (>12 weeks) or recurrent second-trimester losses.
Had prior pregnancy affected by chromosomal or genetic anomaly, or a history suggesting a structural, immune or endocrine problem.

Genetic testing

Products of conception (POC) analysis using chromosomal microarray (or karyotype where indicated) to identify fetal chromosomal abnormalities as a common cause of sporadic loss.
Parental karyotyping when structural chromosomal rearrangements are suspected by history or POC results.

Uterine & structural assessment

Transvaginal ultrasound, saline sonohysterography and diagnostic hysteroscopy to detect congenital anomalies, intrauterine adhesions/polyps or submucous fibroids that can contribute to loss.

Endocrine & metabolic screening

Thyroid function (TSH ± TPO antibodies), fasting glucose / HbA1c and selected hormone tests (as clinically indicated) to identify treatable metabolic or endocrine contributors.

Immunologic & hematologic testing

Antiphospholipid antibody (APLA) panel (lupus anticoagulant, anticardiolipin IgG/IgM, β2-glycoprotein I IgG/IgM) is recommended in RPL evaluation. Routine inherited thrombophilia testing is limited to selected patients per guideline recommendations.

Infection & male-factor assessment

Targeted infectious screening and review of male partner’s semen studies where clinically relevant.

Why choose American Fertility Centre — Sharjah?

Guideline-driven care: Investigations and management aligned with international RPL guidance.

Fast POC and genetic workflows: Rapid sample handling and access to chromosomal microarray for clearer answers.

Multidisciplinary team: Reproductive specialists, genetic counsellors, haematology and pelvic surgeons collaborate on your case.

Compassionate, private care: Sensitive communication, clear follow-up plans and emotional support resources.

Doctor consulting pregnant woman with ultrasound machine in a medical clinic.

Pregnant woman undergoes ultrasound scan by medical professional in hospital room.

A pregnant woman consults with a healthcare professional in a medical clinic.

What to expect at your first visit

Compassionate first appointment: history, prior pregnancy records and pathology review (including any POC if available).

Personalised test plan: we recommend only tests relevant to your history and avoid low-value investigations.

Sample & imaging coordination: POC sampling (if available), blood tests, and scheduled imaging or hysteroscopy.

Multidisciplinary review: results reviewed by a team — reproductive endocrinologist, clinical geneticist/counsellor, andrologist/urologist or haematologist when needed.

Clear follow-up plan: targeted treatment where indicated (e.g., APS management, surgical correction of uterine lesions, genetic counselling, or referral for IVF with PGT if appropriate) and emotional support resources.